Article
Class I associations and frequencies of class II HLA-DRB alleles by RFLP analysis in children with rheumatoid-factor-negative juvenile chronic arthritis.
Rheumatology international - 1 Jan 1993
Brunner H I, Ivaskova E, Haas J P, Andreas A, Keller E, Hoza J, Havelka S, Scholz S, Sierp G, Albert E D
Abstract excerpt
A total of 94 patients with juvenile chronic arthritis (JCA) was tested for HLA class I by serology and for class II by RFLP typing. Early onset JCA (EOPA) is associated with HLA-A2, DR5 and DR8 in both males and females. The combination (joint occurrence) of these JCA associated alleles (A2, DR5, DR8) is frequently seen in patients with chronic iridocyclitis. Late onset pauciarticular disease has an increased...
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