Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A distinct HLA-DRw8 haplotype characterizes patients with juvenile rheumatoid arthritis.

Immunogenetics - 1 Jan 1990

Van Kerckhove C, Melin-Aldana H, Elma M S, Luyrink L, Donnelly P, Taylor J, Maksymowych W P, Lovell D J, Choi E, Glass D N

Abstract excerpt

We studied the first domain of the HLA-DRB1, HLA-DQA1, and HLA-DQB1 loci of 67 HLA-DRw8-positive Caucasians including 43 with early-onset pauciarticular juvenile rheumatoid arthritis (EOPA-JRA, alternatively known as early-onset pauciarticular juvenile chronic arthritis). Serology, restriction fragment length polymorphism (RFLP), and polymerase chain reaction (PCR) oligotyping revealed that 62, including all the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to Genotype
Share to Haplotypes

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to HLA-DQ Antigens

Share to HLA-DR Antigens

Share to Molecular Sequence Data

Share to Polymerase Chain Reaction

Share to Polymorphism, Restriction Fragment Length

Source

Identifiers

PMID: 1979063
DOI: 10.1007/BF00211643

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A distinct HLA-DRw8 haplotype characterizes patients with juvenile rheumatoid arthritis.PMID 1979063Read ↗

HLA-DQA1*0101 haplotypes and disease outcome in early onset pauciarticular juvenile rheumatoid arthritis.Semantic proximity Read ↗

HLA class II alleles and heterogeneity of juvenile rheumatoid arthritis. DRB1*0101 may define a novel subset of the disease.Semantic proximity Read ↗

HLA-DP/DR interaction in early onset pauciarticular juvenile chronic arthritis.Semantic proximity Read ↗

HLA antigens in juvenile arthritis. Pauciarticular and polyarticular juvenile arthritis are immunogenetically distinct.Semantic proximity Read ↗

HLA-DRB1 alleles and juvenile idiopathic arthritis: Diagnostic clues emerging from a meta-analysis.Semantic proximity Read ↗

Immunogenetics of rheumatoid arthritis and juvenile arthritis.Semantic proximity Read ↗

The immunogenetics of juvenile rheumatoid arthritis.Semantic proximity Read ↗

Class I associations and frequencies of class II HLA-DRB alleles by RFLP analysis in children with rheumatoid-factor-negative juvenile chronic arthritis.Semantic proximity Read ↗

Susceptible and protective major histocompatibility complex class II alleles in early-onset pauciarticular juvenile chronic arthritis.Semantic proximity Read ↗

Immunogenetics of juvenile chronic arthritis. I. HLA interaction between A2, DR5/8-DR/DQ, and DPB1*0201 is a general feature of all subsets of early onset pauciarticular juvenile chronic arthritis II. DPB1 polymorphism plays a role in systemic juvenile chronic arthritis.Semantic proximity Read ↗

A model for the role of HLA-DQ molecules in the pathogenesis of juvenile chronic arthritis.Semantic proximity Read ↗

Interaction between HLA-DR and HLA-DP, and between HLA and interleukin 1 alpha in juvenile rheumatoid arthritis indicates heterogeneity of pathogenic mechanisms of the disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.