Article
HLA class II alleles and heterogeneity of juvenile rheumatoid arthritis. DRB1*0101 may define a novel subset of the disease.
Arthritis and rheumatism - 1 Apr 1993
Ploski R, Vinje O, Rønningen K S, Spurkland A, Sørskaar D, Vartdal F, Førre O
Abstract excerpt
OBJECTIVE: To examine the distribution of HLA class II alleles in clinically distinct juvenile rheumatoid arthritis (JRA) subsets. METHODS: We typed 298 patients and 181 controls for HLA-DRB1, DQA1, DQB1, and DPB1 alleles using polymerase chain reaction and oligonucleotide probe techniques. RESUL...
Topics
- Aging
- Alleles
- Antibodies, Antinuclear
- Arthritis, Juvenile
- Child
- Child, Preschool
- Female
- HLA-DP Antigens
- HLA-DQ Antigens
- HLA-DQ alpha-Chains
- HLA-DR Antigens
- HLA-DRB1 Chains
- Histocompatibility Antigens Class II
- Histocompatibility Testing
- Humans
- Infant
- Iridocyclitis
- Male
