[Mutation and expression of Rb gene in human esophageal cancer].

Article

[Mutation and expression of Rb gene in human esophageal cancer].

Zhonghua zhong liu za zhi [Chinese journal of oncology] - 1 Nov 1993

Li H C

Abstract excerpt

The mutation and expression of Rb gene in human esophageal cancer (EC) were investigated by PCR-direct sequencing and Northern blot hybridization. In PCR amplification analysis, in one of 20 (5%) cases of EC was found to have Rb gene deletion in exon 17 and 21; in one of 6 cases of the adjacent n...

Topics

Adult
Base Sequence
Blotting, Northern
DNA, Neoplasm
Esophageal Neoplasms
Exons
Female
Gene Deletion
Gene Expression
Genes, Retinoblastoma
Humans
Male
Middle Aged
Molecular Sequence Data
Mutation
Polymerase Chain Reaction
Suppression, Genetic

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