Article
[Mutation and expression of Rb gene in human esophageal cancer].
Zhonghua zhong liu za zhi [Chinese journal of oncology] - 1 Nov 1993
Li H C
Abstract excerpt
The mutation and expression of Rb gene in human esophageal cancer (EC) were investigated by PCR-direct sequencing and Northern blot hybridization. In PCR amplification analysis, in one of 20 (5%) cases of EC was found to have Rb gene deletion in exon 17 and 21; in one of 6 cases of the adjacent non-tumours tissue was found to have deletion in exon 21. Esophageal carcinoma of human fetus induced by NMBzA had Rb...
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