Article
[Possible significance of novel DNA fragments frequently deleted from tumor cell lines of human esophageal cancer].
Zhonghua zhong liu za zhi [Chinese journal of oncology] - 1 Sept 1997
Hou P, Zheng J, Wang Z
Abstract excerpt
OBJECTIVE: To disclose the genetic susceptibility and carcinogenesis mechanism of esophageal cancer (EC) through finding out tumor suppressor genes. METHODS: Twenty EC tissues paired with adjacent normal mucosa and three high-risk EC families were analysed by PCR and Southern blot with DNA probes (12H2, 33B2, and 33B3) frequently deleted from EC cell lines. RESULTS: In surgical samples, the deletion frequency of...
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