Article
OXA1, a Saccharomyces cerevisiae nuclear gene whose sequence is conserved from prokaryotes to eukaryotes controls cytochrome oxidase biogenesis.
Journal of molecular biology - 3 Jun 1994
Bonnefoy N, Chalvet F, Hamel P, Slonimski P P, Dujardin G
Abstract excerpt
Yeast cells carrying a mutation in the OXA1 nuclear gene are respiratory deficient and lack cytochrome oxidase activity. We successively examined the different steps in the expression of the mitochondrial genes encoding the cytochrome oxidase subunits and apocytochrome b in strains carrying the oxa1-79 mutation. The ox1-79 strains exhibit a total absence of cytochrome aa3 and a decrease in cytochrome b, even in a...
Topics
- Amino Acid Sequence
- Animals
- Bacillus subtilis
- Base Sequence
- Caenorhabditis elegans
- Cell Nucleus
- Chromosome Mapping
- Chromosomes, Fungal
- Cloning, Molecular
- Conserved Sequence
- Cytochrome b Group
