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Article

Multiple defects in the respiratory chain lead to the repression of genes encoding components of the respiratory chain and TCA cycle enzymes.

Journal of molecular biology - 17 Apr 2009

Bourges Ingrid, Mucchielli Marie-Helene, Herbert Christopher J, Guiard Bernard, Dujardin Geneviève, Meunier Brigitte

Abstract excerpt

Respiratory complexes III, IV and V are formed by components of both nuclear and mitochondrial origin and are embedded in the inner mitochondrial membrane. Their assembly requires the auxiliary factor Oxa1, and the absence of this protein has severe consequences on these three major respiratory chain enzymes. We have studied, in the yeast Saccharomyces cerevisiae, the effect of the loss of Oxa1 function and of...

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PMID: 19245817
DOI: 10.1016/j.jmb.2009.02.039

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Multiple defects in the respiratory chain lead to the repression of genes encoding components of the respiratory chain and TCA cycle enzymes.PMID 19245817Read ↗

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The respiratory gene OXA1 has two fission yeast orthologues which together encode a function essential for cellular viability.Semantic proximity Read ↗

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