Article
The transcriptional activator HAP4 is a high copy suppressor of an oxa1 yeast mutation.
Gene - 18 Jul 2005
Hlavacek Otakar, Bourens Myriam, Salone Veronique, Lachacinski Nicole, Lemaire Claire, Dujardin Geneviève
Abstract excerpt
Oxa1p is a key component of the machinery for the insertion of membrane proteins in mitochondria, and in the yeast Saccharomyces cerevisiae, the deletion of OXA1 impairs the biogenesis of the three respiratory complexes of dual genetic origin. Oxa1p is formed from three domains located in the intermembrane space, the inner membrane and the mitochondrial matrix. We have isolated a high copy suppressor able to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
