Article
Mutated c-K-ras in small pancreatic adenocarcinomas.
Pancreas - 1 Mar 1994
Schaeffer B K, Glasner S, Kuhlmann E, Myles J L, Longnecker D S
Abstract excerpt
The objective of this study was to determine whether small human pancreatic adenocarcinomas contain activated c-K-ras as an approach to answering the question of whether c-K-ras mutation is an early change in this disease. Eight pancreatic adenocarcinomas in the range 1.2-3 cm were analyzed for c-K-ras mutation at codon 12 by amplifying the c-K-ras gene around codon 12 out of paraffin-embedded tissue sections...
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