Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutated c-K-ras in small pancreatic adenocarcinomas.

Pancreas - 1 Mar 1994

Schaeffer B K, Glasner S, Kuhlmann E, Myles J L, Longnecker D S

Abstract excerpt

The objective of this study was to determine whether small human pancreatic adenocarcinomas contain activated c-K-ras as an approach to answering the question of whether c-K-ras mutation is an early change in this disease. Eight pancreatic adenocarcinomas in the range 1.2-3 cm were analyzed for c-K-ras mutation at codon 12 by amplifying the c-K-ras gene around codon 12 out of paraffin-embedded tissue sections...

Topics

Adenocarcinoma
Base Sequence
Genes, ras
Humans
Molecular Sequence Data
Mutation
Pancreatic Neoplasms

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 8190717
DOI: 10.1097/00006676-199403000-00004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8190717-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutated c-K-ras in small pancreatic adenocarcinomas.PMID 8190717Read ↗

Detection of codon 12 mutation in the K-ras oncogene in pancreatic tumors.Semantic proximity Read ↗

Mutational activation of the c-K-ras gene in human pancreatic carcinoma.Semantic proximity Read ↗

Activation of c-K-ras mutations in human gastrointestinal tumors.Semantic proximity Read ↗

K-ras oncogene activation in adenocarcinoma of the human pancreas. A study of 82 carcinomas using a combination of mutant-enriched polymerase chain reaction analysis and allele-specific oligonucleotide hybridization.Semantic proximity Read ↗

Patterns of K-ras codon 12 and 13 mutations found in pancreatic adenocarcinoma of 30 Chinese patients by microdissection, PCR and direct sequencing.Semantic proximity Read ↗

Detection of point mutations in the K-ras oncogene at codon 12 in pure pancreatic juice for diagnosis of pancreatic carcinoma.Semantic proximity Read ↗

Clinical application of ras gene mutation for diagnosis of pancreatic adenocarcinoma.Semantic proximity Read ↗

Detection of pancreatic carcinoma: diagnostic value of K-ras mutations in circulating DNA from serum.Semantic proximity Read ↗

Reassessment of K-ras mutations at codon 12 by direct PCR and sequencing from tissue microdissection in human pancreatic adenocarcinomas.Semantic proximity Read ↗

K‐<i>ras</i> codon 12 mutations in Barrett’s oesophagus and adenocarcinomas of the oesophagus and oesophagogastric junctionSemantic proximity Read ↗

Values of mutations of K-ras oncogene at codon 12 in detection of pancreatic cancer: 15-year experience.Semantic proximity Read ↗

Mutations in the Kirsten-ras oncogene are common but lack correlation with prognosis and tumor stage in human pancreatic carcinoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.