Article
A new VSG expression site-associated gene (ESAG) in the promoter region of Trypanosoma brucei encodes a protein with 10 potential transmembrane domains.
Molecular and biochemical parasitology - 1 Jan 1994
Gottesdiener K M
Abstract excerpt
In Trypanosoma brucei bloodstream variants 118 cl 1, 118a and 118b, the actively transcribed VSG gene expression site (ES) is located on a 1.5 Mb chromosome. The promoter region for this polycistronic transcription unit is unusual in that there are two, tandemly located, promoter repeats, each 2.1 kb in size, separated by 13 kb of intervening DNA. As previously shown, at inactivation of this ES, the promoter...
Topics
- Amino Acid Sequence
- Animals
- Chromosome Mapping
- Cloning, Molecular
- DNA, Protozoan
- Gene Expression
- Genes, Protozoan
- Genetic Variation
- Membrane Proteins
- Molecular Sequence Data
- Promoter Regions, Genetic