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Article

TbISWI regulates multiple polymerase I (Pol I)-transcribed loci and is present at Pol II transcription boundaries in Trypanosoma brucei.

Eukaryotic cell - 1 Jul 2011

Stanne Tara M, Kushwaha Manish, Wand Matthew, Taylor Jesse E, Rudenko Gloria

Abstract excerpt

The unicellular eukaryote Trypanosoma brucei is unusual in having very little transcriptional control. The bulk of the T. brucei genome is constitutively transcribed by RNA polymerase II (Pol II) as extensive polycistronic transcription units. Exceptions to this rule include several RNA Pol I transcription units such as the VSG expression sites (ESs), which are mono-allelically expressed. TbISWI, a member of the...

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Identifiers

PMID: 21571922
DOI: 10.1128/EC.05048-11
PMCID: PMC3147422

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