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Article

TbISWI regulates multiple polymerase I (Pol I)-transcribed loci and is present at Pol II transcription boundaries in Trypanosoma brucei.

Eukaryotic cell - 1 Jul 2011

Stanne Tara M, Kushwaha Manish, Wand Matthew, Taylor Jesse E, Rudenko Gloria

Abstract excerpt

The unicellular eukaryote Trypanosoma brucei is unusual in having very little transcriptional control. The bulk of the T. brucei genome is constitutively transcribed by RNA polymerase II (Pol II) as extensive polycistronic transcription units. Exceptions to this rule include several RNA Pol I transcription units such as the VSG expression sites (ESs), which are mono-allelically expressed. TbISWI, a member of the...

Topics

Adenosine Triphosphatases
Alleles
Chromatin Assembly and Disassembly
Chromatin Immunoprecipitation
DNA-Binding Proteins
Flow Cytometry
Gene Expression Regulation, Fungal
Histones
RNA Polymerase I
RNA Polymerase II

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Reverse Transcriptase Polymerase Chain Reaction

Transcription Factors

Transcription, Genetic

Transcriptional Activation

Trypanosoma brucei brucei

Source

Open in PubMed Open full text

Identifiers

PMID: 21571922
DOI: 10.1128/EC.05048-11
PMCID: PMC3147422

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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