Immunoglobulin somatic variation; studies of receptor editing in a human B cell lymphoma.

Abstract excerpt

In order to study mechanisms of immunoglobulin somatic variation in committed immunoglobulin (Ig) expressing B cells, we used the fluorescent activated cell sorter to isolate rare variants from a surface Ig positive (sIg+) diffuse large cell B lymphoma cell line (mu lambda+). These variants were...

Topics

• Amino Acid Sequence
• Base Sequence
• Gene Rearrangement
• Genes, Immunoglobulin
• Humans
• Immunoglobulin Variable Region
• Lymphoma, B-Cell
• Molecular Sequence Data
• Mutation