Article
Myelomonocytic crisis with t(5;17) and a p53 mutation in a patient with chronic myelogenous leukemia.
American journal of hematology - 1 Apr 1994
Nakagawa H, Fujii H, Nakai H, Inazawa J, Misawa S
Abstract excerpt
We report a 64-year-old Japanese man with chronic myelogenous leukemia (CML) who expired with myelomonocytic crisis. Cytogenetic analyses of chronic phase (CP) and accelerated phase (AP) cells revealed a Philadelphia chromosome and an isochromosome for the long arm of chromosome 17, i(17q). This karyotype was replaced by another karyotype in blast crisis (BC), resulting in near triploidy with t(5;17) (p15;p11)...
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