Article
Rules for alpha-helix termination by glycine.
Science (New York, N.Y.) - 20 May 1994
Aurora R, Srinivasan R, Rose G D
Abstract excerpt
A predictive rule for protein folding is presented that involves two recurrent glycine-based motifs that cap the carboxyl termini of alpha helices. In proteins, helices that terminated in glycine residues were found predominantly in one of these two motifs. These glycine structures had a characteristic pattern of polar and apolar residues. Visual inspection of known helical sequences was sufficient to distinguish...
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