Are the same or different amino acid residues responsible for correct and incorrect protein folding?

Abstract excerpt

It has been shown for 20 proteins that amino acid residues included into the protein folding nucleus, determined experimentally, are often involved in the theoretically determined amyloidogenic fragments. For 18 proteins, Phi-values indicative of the extent of residue involvement into the folding nucleus are on average higher for amino acid residues within amyloidogenic regions. Amyloidogenic fragments were...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Amino Acids
• Share to Amyloid
• Share to Databases, Protein