Article
Erythromycin, lincosamides, peptidyl-tRNA dissociation, and ribosome editing.
Molecular & general genetics : MGG - 1 Apr 1994
Menninger J R, Coleman R A, Tsai L N
Abstract excerpt
Inaccurate protein synthesis produces unstable beta-galactosidase, whose activity is rapidly lost at high temperature. Erythromycin, lincomycin, clindamycin, and celesticetin were shown to counteract the error-inducing effects of streptomycin on beta-galactosidase synthesized in the antibiotic-hypersensitive Escherichia coli strain DB-11 Met-. Newly synthesized beta-galactosidase was more easily inactivated by...
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