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[Stability of normal, abnormal and recombinant proteins in Escherichia coli strains deficient for intracellular proteinase La--the product of the lon gene].

Molekuliarnaia biologiia - 1 Jan 2000

Ryzhavskaia A S, Kaĭdalova N V, Anukhin Iu M, Kliachko E V, Livshits V A

Abstract excerpt

Escherichia coli Lon-mutants deficient in intracellular protease La have been isolated. The rate of degradation of normal cellular proteins was 1.5-2-fold lower in Lon-mutants as compared with that of the wild type strain. The rate of degradation of canavanine-containing abnormal proteins, as well as foreign proteins was significantly higher in E. coli than that of normal proteins. Lon-mutants possessed...

Topics

ATP-Dependent Proteases
Bacterial Proteins
Canavanine
Cloning, Molecular
Escherichia coli
Escherichia coli Proteins
Heat-Shock Proteins
Hydrolysis
Interferon Type I
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Protease La

Recombinant Proteins

Serine Endopeptidases

Source

Identifiers

PMID: 3287135

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-3287135-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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[Stability of normal, abnormal and recombinant proteins in Escherichia coli strains deficient for intracellular proteinase La--the product of the lon gene].PMID 3287135Read ↗

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