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Article

Purification and characterisation of a brain-derived neurotrophic factor/neurotrophin-3 (BDNF/NT-3) heterodimer.

European journal of biochemistry - 15 Apr 1994

Jungbluth S, Bailey K, Barde Y A

Abstract excerpt

The neurotrophins nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), and neurotrophin-3 (NT-3) are known to exist in solution as non-covalently linked homodimeric proteins. The recent elucidation of the crystal structure of the NGF homodimer, as well as the conservation of structural motifs in the neurotrophins, raised the possibility that neurotrophin heterodimers might also occur. The...

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Source

Identifiers

PMID: 8174548
DOI: 10.1111/j.1432-1033.1994.tb18780.x

Genes

BDNF
NGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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