Article
The dual nature of neurotrophins.
BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Jun 2006
Schweigreiter Rüdiger
Abstract excerpt
Neurotrophins are a small family of dimeric secretory proteins in vertebrate neurons with a broad spectrum of functions. They are generated as pro-proteins with a functionality that is distinct from the proteolytically processed form. The cellular responses of neurotrophins are mediated by three different types of receptor proteins, the receptor tyrosine kinases of the Trk family, the neurotrophin receptor...
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