Structural determinants of neurotrophin action.

Abstract excerpt

Five decades of research on NGF have led to the discovery of a small family of evolutionarily conserved proteins, which have vital functions in the survival and neuronal development of specific neuronal populations. The generation of mice lacking neurotrophin expression has recapitulated classic...

Topics

• Animals
• Humans
• Models, Molecular
• Molecular Structure
• Mutation
• Nerve Growth Factors
• Receptors, Nerve Growth Factor
• Signal Transduction