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Article

Genetic identification of Mcs-1, a rat mammary carcinoma suppressor gene.

Cancer research - 15 May 1994

Hsu L C, Kennan W S, Shepel L A, Jacob H J, Szpirer C, Szpirer J, Lander E S, Gould M N

Abstract excerpt

Women have inherited differences in their susceptibility to breast cancer, but the genes underlying this variation are difficult to identify. We have approached the problem of identifying breast cancer susceptibility genes by using a rat model. Inbred rat strains display differential susceptibilities to mammary carcinogenesis; the Copenhagen (COP) rat is resistant, while the Wistar-Furth (WF) rat is susceptible...

Topics

9,10-Dimethyl-1,2-benzanthracene
Animals
Chromosome Mapping
Female
Genes, Tumor Suppressor
Genetic Markers
In Situ Hybridization, Fluorescence
Mammary Neoplasms, Experimental
Phenotype
Rats
Rats, Inbred Strains

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 8168109

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8168109-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Genetic identification of Mcs-1, a rat mammary carcinoma suppressor gene.PMID 8168109Read ↗

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