Article
Genetic loci controlling breast cancer susceptibility in the Wistar-Kyoto rat.
Genetics - 1 Jan 2001
Lan H, Kendziorski C M, Haag J D, Shepel L A, Newton M A, Gould M N
Abstract excerpt
In this study, the Wistar-Kyoto (WKy) rat was genetically characterized for loci that modify susceptibility to mammary carcinogenesis. We used a genetic backcross between resistant WKy and susceptible Wistar-Furth (WF) rats as a panel for linkage mapping to genetically identify mammary carcinoma susceptibility (Mcs) loci underlying the resistance of the WKy rat. Rats were phenotyped for DMBA-induced mammary...
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