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Article

Rat Mcs1b is concordant to the genome-wide association-identified breast cancer risk locus at human 5q11.2 and MIER3 is a candidate cancer susceptibility gene.

Cancer research - 15 Nov 2012

denDekker Aaron D, Xu Xin, Vaughn M Derek, Puckett Aaron H, Gardner Louis L, Lambring Courtney J, Deschenes Lucas, Samuelson David J

Abstract excerpt

Low-penetrance alleles associated with breast cancer risk have been identified in population-based studies. Most risk loci contain either no or multiple potential candidate genes. Rat mammary carcinoma susceptibility 1b (Mcs1b) is a quantitative trait locus on RN02 that confers decreased susceptibility when Copenhagen (COP)-resistant alleles are introgressed into a Wistar Furth (WF)-susceptible genome. Five...

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Identifiers

PMID: 22993404
DOI: 10.1158/0008-5472.CAN-12-0748
PMCID: PMC3500408

Genes

MIER3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Rat Mcs1b is concordant to the genome-wide association-identified breast cancer risk locus at human 5q11.2 and MIER3 is a candidate cancer susceptibility gene.PMID 22993404Read ↗

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