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Article

A mammary cancer suppressor gene and its site of action in the rat.

Cancer research - 15 Mar 1991

Isaacs J T

Abstract excerpt

Fifty-day-old female rats of the inbred Osborne-Mendel (OM) and Copenhagen (COP) strains were exposed to a single dose of either of 2 highly effective mammary chemical carcinogens, 7,12-dimethylbenz[a] anthracene (DMBA) or 1-methyl-1-nitrosourea (MNU). Female OM rats are highly susceptible to both of these carcinogens developing greater than 5 mammary adenocarcinomas per rat following a single exposure to either...

Topics

9,10-Dimethyl-1,2-benzanthracene
Alleles
Animals
Female
Genes, Tumor Suppressor
Homozygote
Mammary Neoplasms, Experimental
Methylnitrosourea
Mice
Rats
Rats, Inbred Strains

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 1900214

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1900214-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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