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Article

Osmotic stress and the yeast cytoskeleton: phenotype-specific suppression of an actin mutation.

The Journal of cell biology - 1 Aug 1992

Chowdhury S, Smith K W, Gustin M C

Abstract excerpt

In the yeast Saccharomyces cerevisiae, actin filaments function to direct cell growth to the emerging bud. Yeast has a single essential actin gene, ACT1. Diploid cells containing a single copy of ACT1 are osmosensitive (Osms), i.e., they fail to grow in high osmolarity media (D. Shortle, unpublished observations cited by Novick, P., and D. Botstein. 1985. Cell. 40:415-426). This phenotype suggests that an...

Topics

Actins
Cytoskeleton
Diploidy
Kinetics
Microfilament Proteins
Microscopy, Fluorescence
Osmotic Pressure
Phenotype
Saccharomyces cerevisiae
Suppression, Genetic

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Identifiers

PMID: 1639843
DOI: 10.1083/jcb.118.3.561
PMCID: PMC2289551

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1639843-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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