Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Neutrophil lysosomal dysfunctions in mutant C57 Bl/6J mice: interstrain variations in content of lysosomal elastase, cathepsin G and their inhibitors.

The Biochemical journal - 1 Apr 1994

Gardi C, Cavarra E, Calzoni P, Marcolongo P, de Santi M, Martorana P A, Lungarella G

Abstract excerpt

In this paper we report the serum antiprotease screening and the biochemical and functional characteristics of neutrophils in a variety of mouse strains with different susceptibilities for developing a protease-mediated injury. C57Bl/6J mice and their mutants tight-skin and pallid have a lower serum elastase inhibitory capacity (-30, -65 and -70% respectively) than other inbred strains (i.e. NMRI and Balb/c,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Electrophoresis, Polyacrylamide Gel

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mice, Inbred Strains

Share to Microscopy, Electron

Share to Molecular Sequence Data

Share to Mutation

Share to Serine Endopeptidases

Source

Open in PubMed Open full text

Identifiers

PMID: 8166647
DOI: 10.1042/bj2990237
PMCID: PMC1138047

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Neutrophil lysosomal dysfunctions in mutant C57 Bl/6J mice: interstrain variations in content of lysosomal elastase, cathepsin G and their inhibitors.PMID 8166647Read ↗

Effects of the beige mutation on respiratory tract infection with Pseudomonas aeruginosa in mice.Semantic proximity Read ↗

Nlrp12 mutation causes C57BL/6J strain-specific defect in neutrophil recruitment.Semantic proximity Read ↗

Mouse Models and Tools for the in vivo Study of NeutrophilsSemantic proximity Read ↗

Myeloid conditional deletion and transgenic models reveal a threshold for the neutrophil survival factor Serpinb1.Semantic proximity Read ↗

Towards specific functions of lysosomal cysteine peptidases: phenotypes of mice deficient for cathepsin B or cathepsin L.Semantic proximity Read ↗

Neutrophil elastase-deficient mice form neutrophil extracellular traps in an experimental model of deep vein thrombosis.Semantic proximity Read ↗

Widespread discrepancy in Nnt genotypes and genetic backgrounds complicates granzyme A and other knockout mouse studies.Semantic proximity Read ↗

Astrogliosis and behavioral changes in mice lacking the neutral cysteine protease bleomycin hydrolase.Semantic proximity Read ↗

Lysosomal acid lipase deficiency causes respiratory inflammation and destruction in the lung.Semantic proximity Read ↗

A severely affected MRL/Lpr mouse exhibits a divergent clinical–immune profile associated with a profound metabolic alterationSemantic proximity Read ↗

Defect in neutrophil killing and increased susceptibility to infection with nonpathogenic gram-positive bacteria in peptidoglycan recognition protein-S (PGRP-S)-deficient mice.Semantic proximity Read ↗

Relationships between early inflammatory response to bleomycin and sensitivity to lung fibrosis: a role for dipeptidyl-peptidase I and tissue inhibitor of metalloproteinase-3?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.