Article
Neutrophil lysosomal dysfunctions in mutant C57 Bl/6J mice: interstrain variations in content of lysosomal elastase, cathepsin G and their inhibitors.
The Biochemical journal - 1 Apr 1994
Gardi C, Cavarra E, Calzoni P, Marcolongo P, de Santi M, Martorana P A, Lungarella G
Abstract excerpt
In this paper we report the serum antiprotease screening and the biochemical and functional characteristics of neutrophils in a variety of mouse strains with different susceptibilities for developing a protease-mediated injury. C57Bl/6J mice and their mutants tight-skin and pallid have a lower se...
Topics
- Amino Acid Sequence
- Animals
- Cathepsin G
- Cathepsins
- Cytosol
- Electrophoresis, Polyacrylamide Gel
- Leukocyte Elastase
- Lysosomes
- Male
- Mice
- Mice, Inbred Strains
- Microscopy, Electron
- Molecular Sequence Data
- Mutation
- Neutrophils