Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Neutrophil elastase-deficient mice form neutrophil extracellular traps in an experimental model of deep vein thrombosis.

Journal of thrombosis and haemostasis : JTH - 1 Mar 2016

Martinod K, Witsch T, Farley K, Gallant M, Remold-O'Donnell E, Wagner D D

Abstract excerpt

UNLABELLED: ESSENTIALS: Neutrophil elastase (NE) plays a role in extracellular trap formation (NETosis) triggered by microbes. The contribution of NE was evaluated in mouse NETosis models of sterile inflammation and thrombosis. NE is not required for mouse neutrophil NET production in vitro with non-infectious stimuli. NE deficiency had no significant effect on thrombosis in the inferior vena cava stenosis model....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Extracellular Traps
Share to Ionomycin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Leukocyte Elastase

Share to Mice, Knockout

Share to Neutrophil Activation

Share to Neutrophils

Share to Tetradecanoylphorbol Acetate

Share to Venous Thrombosis

Source

Open in PubMed Open full text

Identifiers

PMID: 26712312
DOI: 10.1111/jth.13239
PMCID: PMC4785059

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Neutrophil elastase-deficient mice form neutrophil extracellular traps in an experimental model of deep vein thrombosis.PMID 26712312Read ↗

NLRP3 Inflammasome Assembly in Neutrophils Is Supported by PAD4 and Promotes NETosis Under Sterile ConditionsSemantic proximity Read ↗

COVID-19 Pathology Sheds New Light on Balance between Neutrophil Proteases and Their InhibitorsSemantic proximity Read ↗

The inhibitory effect of secretory leukocyte protease inhibitor (SLPI) on formation of neutrophil extracellular trapsSemantic proximity Read ↗

The Pathophysiological Role of Neutrophil Extracellular Traps in Inflammatory DiseasesSemantic proximity Read ↗

Intact Toll-like receptor 9 signaling in neutrophils modulates normal thrombogenesis in mice.Semantic proximity Read ↗

Methods for the Assessment of NET Formation: From Neutrophil Biology to Translational ResearchSemantic proximity Read ↗

A serpinB1 regulatory mechanism is essential for restricting neutrophil extracellular trap generation.Semantic proximity Read ↗

Extracellular DNA NET-Works With Dire Consequences for HealthSemantic proximity Read ↗

The coming of age of neutrophil extracellular traps in thrombosis: Where are we now and where are we headed?Semantic proximity Read ↗

Recent progress in the mechanistic understanding of NET formation in neutrophilsSemantic proximity Read ↗

Proteins derived from neutrophil extracellular traps may serve as self-antigens and mediate organ damage in autoimmune diseasesSemantic proximity Read ↗

A GPVI-platelet-neutrophil-NET axis drives systemic sclerosisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.