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Article

Astrogliosis and behavioral changes in mice lacking the neutral cysteine protease bleomycin hydrolase.

Neuroscience - 25 May 2007

Montoya S E, Thiels E, Card J P, Lazo J S

Abstract excerpt

Bleomycin hydrolase (BLMH) is a multifaceted neutral cysteine protease with a suggested role in antigen presentation, homocysteine-thiolactone metabolism, and Alzheimer's disease pathogenesis. Deletion of the protease in mice results in increased neonatal mortality and dermatopathology. Immunohistochemical and behavioral studies of BLMH knockout mice were undertaken to further evaluate the role of the protease in...

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Identifiers

PMID: 17391860
DOI: 10.1016/j.neuroscience.2007.02.027
PMCID: PMC2586062

Genes

BLMH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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