Article
The yeast MOT2 gene encodes a putative zinc finger protein that serves as a global negative regulator affecting expression of several categories of genes, including mating-pheromone-responsive genes.
Molecular and cellular biology - 1 May 1994
Irie K, Yamaguchi K, Kawase K, Matsumoto K
Abstract excerpt
The STE4 gene encodes the beta subunit of a heterotrimeric G protein that is an essential component of the pheromone signal transduction pathway. To identify downstream component(s) of Ste4, we sought pseudo-revertants that restored mating competence to ste4 mutants. The suppressor mot2 was isolated as a recessive mutation that restored conjugational competence to a temperature-sensitive ste4 mutant and...
Topics
- Amino Acid Sequence
- Base Sequence
- Flow Cytometry
- Fungal Proteins
- Gene Deletion
- Gene Expression Regulation, Fungal
- Genes, Fungal
- Genes, Regulator
- Genotype
- Macromolecular Substances