Combinatorial control required for the specificity of yeast MAPK signaling.

doi:10.1126/science.275.5304.1314

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Combinatorial control required for the specificity of yeast MAPK signaling.

Science (New York, N.Y.) - 28 Feb 1997

Madhani H D, Fink G R

Abstract excerpt

In yeast, an overlapping set of mitogen-activated protein kinase (MAPK) signaling components controls mating, haploid invasion, and pseudohyphal development. Paradoxically, a single downstream transcription factor, Ste12, is necessary for the execution of these distinct programs. Developmental sp...

Topics

Calcium-Calmodulin-Dependent Protein Kinases
DNA-Binding Proteins
Enhancer Elements, Genetic
Fungal Proteins
Intracellular Signaling Peptides and Proteins
MAP Kinase Kinase Kinases
Mitogen-Activated Protein Kinase Kinases
Mutation
Protein Kinases
Protein Serine-Threonine Kinases
Retroelements
Saccharomyces cerevisiae
Saccharomyces cerevisiae Proteins
Schizosaccharomyces pombe Proteins
Signal Transduction
Transcription Factors
Transcription, Genetic

Source

Open in PubMed

Identifiers

PMID: 9036858
DOI: 10.1126/science.275.5304.1314

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9036858-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics