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Article

STE50, a novel gene required for activation of conjugation at an early step in mating in Saccharomyces cerevisiae.

Molecular & general genetics : MGG - 1 Dec 1992

Rad M R, Xu G, Hollenberg C P

Abstract excerpt

A new gene, STE50, which plays an essential role in cell differentiation in Saccharomyces cerevisiae was detected and analysed. STE50 expression is not cell type-specific and its expression in MATa and MAT alpha cells is unaffected by pheromones. When present on a high copy number plasmid, STE50 causes supersensitivity to alpha-pheromone, and increases the level of alpha-pheromone-induced transcription of FUS1 in...

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Identifiers

PMID: 1494345
DOI: 10.1007/BF00279653

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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STE50, a novel gene required for activation of conjugation at an early step in mating in Saccharomyces cerevisiae.PMID 1494345Read ↗

Regulation of the yeast pheromone response pathway by G protein subunits.Semantic proximity Read ↗

Ste50p sustains mating pheromone-induced signal transduction in the yeast Saccharomyces cerevisiae.Semantic proximity Read ↗

Overexpression of the STE4 gene leads to mating response in haploid Saccharomyces cerevisiae.Semantic proximity Read ↗

Mutational activation of the STE5 gene product bypasses the requirement for G protein beta and gamma subunits in the yeast pheromone response pathway.Semantic proximity Read ↗

The Leu-132 of the Ste4(Gbeta) subunit is essential for proper coupling of the G protein with the Ste2 alpha factor receptor during the mating pheromone response in yeast.Semantic proximity Read ↗

Genetic relationships between the G protein beta gamma complex, Ste5p, Ste20p and Cdc42p: investigation of effector roles in the yeast pheromone response pathway.Semantic proximity Read ↗

Cloning of Saccharomyces cerevisiae STE5 as a suppressor of a Ste20 protein kinase mutant: structural and functional similarity of Ste5 to Far1.Semantic proximity Read ↗

Mating in Saccharomyces cerevisiae: the role of the pheromone signal transduction pathway in the chemotropic response to pheromone.Semantic proximity Read ↗

Role of the ABC transporter Ste6 in cell fusion during yeast conjugation.Semantic proximity Read ↗

Ste50p is involved in regulating filamentous growth in the yeast Saccharomyces cerevisiae and associates with Ste11p.Semantic proximity Read ↗

Autocrine activation of the pheromone response pathway in matalpha2- cells is attenuated by SST2- and ASG7-dependent mechanisms.Semantic proximity Read ↗

Association of the yeast pheromone response G protein beta gamma subunits with the MAP kinase scaffold Ste5p.Semantic proximity Read ↗

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