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Article

Extragenic suppressors that rescue defects in the heat stress response of the budding yeast mutant tom1.

Molecular & general genetics : MGG - 1 Jan 2000

Sasaki T, Toh-e A, Kikuchi Y

Abstract excerpt

The TOM1 gene codes for a so-called HECT protein, a putative ubiquitin ligase, in Saccharomyces cerevisiae. Deletion of the entire gene (tom1-10) or the sequence encoding the HECT domain (tom1-2) causes temperature sensitivity for growth. Here we report the isolation of extragenic, recessive suppressors of tom1-2, which were designated tmr (for tom1 revertant) mutations. These were classified into eight...

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Source

Identifiers

PMID: 10660055
DOI: 10.1007/pl00008662

Genes

TOM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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