Article
Mutations of Ki-ras oncogene codon 12 in betel quid chewing-related human oral squamous cell carcinoma in Taiwan.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology - 1 Feb 1994
Kuo M Y, Jeng J H, Chiang C P, Hahn L J
Abstract excerpt
In Taiwan, there are two million people who have a betel quid chewing habit, and approximately 80% of all oral cancer deaths are associated with this habit. To investigate the incidence and types of Ki-ras codon 12 mutations in oral cancer associated with betel quid chewing, we used a sensitive m...
Topics
- Adult
- Areca
- Base Sequence
- Carcinoma, Squamous Cell
- Codon
- DNA Mutational Analysis
- DNA, Neoplasm
- Genes, ras
- Humans
- Male
- Middle Aged
- Molecular Sequence Data
- Mouth Mucosa
- Mouth Neoplasms
- Mutation
- Plants, Medicinal
- Polymerase Chain Reaction
- Substance-Related Disorders