Article
Genuine Bayesian multiallelic significance test for the Hardy-Weinberg equilibrium law.
Genetics and molecular research : GMR - 31 Oct 2006
Pereira C A B, Nakano F, Stern J M, Whittle M R
Abstract excerpt
Statistical tests that detect and measure deviation from the Hardy-Weinberg equilibrium (HWE) have been devised but are limited when testing for deviation at multiallelic DNA loci is attempted. Here we present the full Bayesian significance test (FBST) for the HWE. This test depends neither on asymptotic results nor on the number of possible alleles for the particular locus being evaluated. The FBST is based on...
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