Article
Regulation of stringent mitochondrial transcription in yeast following amino-acid deprivation.
Gene - 8 Apr 1994
McEntee C M, Cantwell-Ibdah R, Hudson A P
Abstract excerpt
In the yeast Saccharomyces cerevisiae, a phenotypically identical stringent response is induced by either nutritional downshift or starvation for a required auxotrophic amino acid (aa); in each case, the response selectively includes transcriptional curtailment for the mitochondrial (mt) genome. We have shown previously that the downshift-induced mt stringent response is governed by changing cellular cyclic AMP...
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