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Article

Regulation of stringent mitochondrial transcription in yeast following amino-acid deprivation.

Gene - 8 Apr 1994

McEntee C M, Cantwell-Ibdah R, Hudson A P

Abstract excerpt

In the yeast Saccharomyces cerevisiae, a phenotypically identical stringent response is induced by either nutritional downshift or starvation for a required auxotrophic amino acid (aa); in each case, the response selectively includes transcriptional curtailment for the mitochondrial (mt) genome. We have shown previously that the downshift-induced mt stringent response is governed by changing cellular cyclic AMP...

Topics

Amino Acids
Culture Media
Cyclic AMP
Cyclic AMP-Dependent Protein Kinases
Down-Regulation
Gene Expression Regulation, Fungal
Mitochondria
Mutation
Saccharomyces cerevisiae
Transcription, Genetic

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Identifiers

PMID: 8163164
DOI: 10.1016/0378-1119(94)90140-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8163164-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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