Article
Glucose-induced hyperaccumulation of cyclic AMP and defective glucose repression in yeast strains with reduced activity of cyclic AMP-dependent protein kinase.
Molecular and cellular biology - 1 Sept 1990
Mbonyi K, van Aelst L, Argüelles J C, Jans A W, Thevelein J M
Abstract excerpt
Addition of glucose or related fermentable sugars to derepressed cells of the yeast Saccharomyces cerevisiae triggers a RAS-mediated cyclic AMP (cAMP) signal that induces a protein phosphorylation cascade. In yeast mutants (tpk1w1, tpk2w1, and tpk3w1) containing reduced activity of cAMP-dependent...
Topics
- Adenosine Triphosphate
- Enzyme Activation
- Enzyme Repression
- Genotype
- Glucose
- Hydrogen-Ion Concentration
- Kinetics
- Protein Kinases
- Saccharomyces cerevisiae
- Signal Transduction
- Trehalase