Article
Regulation of phospholipid biosynthesis in Saccharomyces cerevisiae by cyclic AMP-dependent protein kinase.
Journal of bacteriology - 1 Feb 1990
Kinney A J, Bae-Lee M, Panghaal S S, Kelley M J, Gaynor P M, Carman G M
Abstract excerpt
The addition of cyclic AMP (cAMP) to Saccharomyces cerevisiae cyr1 mutant cells resulted in an increase in the rate of phosphatidylinositol synthesis at the expense of phosphatidylserine synthesis. The decrease in phosphatidylserine synthesis correlated with the down regulation of phosphatidylserine synthase activity by cAMP-dependent protein kinase phosphorylation. The increase in phosphatidylinositol synthesis...
Topics
- CDPdiacylglycerol-Serine O-Phosphatidyltransferase
- Cyclic AMP
- Homeostasis
- Kinetics
- Mutation
- Phosphatidylinositols
- Phosphatidylserines
- Phospholipids
- Phosphorylation
- Protein Kinases
- Saccharomyces cerevisiae