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Article

Transcription of the yeast mitochondrial genome requires cyclic AMP.

Molecular & general genetics : MGG - 1 Oct 1993

McEntee C M, Cantwell R, Rahman M U, Hudson A P

Abstract excerpt

Using various mutant strains and nutritional manipulations, we investigated a potential role for cyclic AMP (cAMP) in the regulation of mitochondrial (mt) gene expression in the yeast Saccharomyces cerevisiae. In RAS mutants known to have either abnormally low or high cellular levels of this nucleotide, we show that both mt transcription rate and overall mt transcript levels vary directly with cellular cAMP...

Topics

Cyclic AMP
Cyclic AMP-Dependent Protein Kinases
DNA, Mitochondrial
Genome, Fungal
Glucose
Mutation
RNA, Messenger
Saccharomyces cerevisiae
Transcription, Genetic

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 8232206
DOI: 10.1007/BF00280219

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8232206-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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