Inhibition of G1 cyclin activity by the Ras/cAMP pathway in yeast.

doi:10.1038/371342a0

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Article

Inhibition of G1 cyclin activity by the Ras/cAMP pathway in yeast.

Nature - 22 Sept 1994

Tokiwa G, Tyers M, Volpe T, Futcher B

Abstract excerpt

In the yeast Saccharomyces cerevisiae, commitment to cell division (Start) requires growth to a critical cell size. The G1 cyclins Cln1, Cln2 and Cln3 activate the Cdc28 protein kinase and are rate-limiting activators of Start. When glucose is added to cells growing in a poor carbon source, the c...

Topics

Cell Division
Cyclic AMP
Cyclic AMP-Dependent Protein Kinases
Cyclins
Fungal Proteins
G1 Phase
Gene Expression Regulation, Fungal
Glucose
Mutation
Saccharomyces cerevisiae
Signal Transduction
ras Proteins

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