Alleles of highly homologous rat T cell receptor beta-chain variable segments 8.2 and 8.4: strain-specific expression, reactivity to superantigens, and binding of the mAb R78.

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Article

Alleles of highly homologous rat T cell receptor beta-chain variable segments 8.2 and 8.4: strain-specific expression, reactivity to superantigens, and binding of the mAb R78.

Journal of immunology (Baltimore, Md. : 1950) - 15 Nov 1996

Asmuss A, Hofmann K, Hochgrebe T, Giegerich G, Hünig T, Herrmann T

Abstract excerpt

This study addresses the molecular basis of a Tcrb-V polymorphism in the reactivity to the superantigens staphylococcus enterotoxin B (SEB) and the mtv-7 sag (MIs1a) of T cells recognized by the mAb R78, which reacts with the T cell receptor beta-chain variable segment 8.2 (Tcrb-V8.2) of Lewis (L...

Topics

Alleles
Amino Acid Sequence
Animals
Antibodies, Monoclonal
Base Sequence
Binding Sites, Antibody
Female
Molecular Sequence Data
Rats
Rats, Inbred Lew
Receptors, Antigen, T-Cell, alpha-beta
Species Specificity
Superantigens

Source

Open in PubMed

Identifiers

PMID: 8906819

Genes

CDR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8906819-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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