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Article

H-ras mutations in human pituitary carcinoma metastases.

The Journal of clinical endocrinology and metabolism - 1 Apr 1994

Pei L, Melmed S, Scheithauer B, Kovacs K, Prager D

Abstract excerpt

Molecular mechanisms of pituitary tumorigenesis were studied using Polymerase chain reaction-single stranded conformational polymorphism with DNA sequencing to identify potential mutations in the ras protooncogenes and the tumor suppressor gene p53 in invasive pituitary adenomas and carcinomas. Sequencing of exons 5 through 8 of the p53 gene revealed no mutations, nor were mutations detected in the N- or K-ras...

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Identifiers

PMID: 8157709
DOI: 10.1210/jcem.78.4.8157709

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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