Large-scale oligonucleotide typing for HLA-DRB1/3/4 and HLA-DQB1 is highly accurate, specific, and reliable.

doi:10.1111/j.1399-0039.1993.tb02191.x

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Large-scale oligonucleotide typing for HLA-DRB1/3/4 and HLA-DQB1 is highly accurate, specific, and reliable.

Tissue antigens - 1 Nov 1993

Ng J, Hurley C K, Baxter-Lowe L A, Chopek M, Coppo P A, Hegland J, KuKuruga D, Monos D, Rosner G, Schmeckpeper B

Abstract excerpt

DNA typing of HLA class II alleles of the DRB1/3/4 and DQB1 loci using sequence-specific oligonucleotide probes and polymerase chain reaction-amplified DNA was used for the large-scale typing of donors for the National Marrow Donor Program unrelated donor registry. The results of quality control analysis for the first 7 months of the project show the typing to be highly accurate, specific, and reliable. The...

Topics

Alleles
DNA
HLA-DQ Antigens
HLA-DQ beta-Chains
HLA-DR Antigens
HLA-DRB1 Chains
HLA-DRB3 Chains
HLA-DRB4 Chains
Histocompatibility Antigens Class II
Histocompatibility Testing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Oligonucleotide Probes

Oligonucleotides

Polymerase Chain Reaction

Quality Control

Registries

Tissue Donors

Source

Open in PubMed

Identifiers

PMID: 8146858
DOI: 10.1111/j.1399-0039.1993.tb02191.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8146858-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Large-scale oligonucleotide typing for HLA-DRB1/3/4 and HLA-DQB1 is highly accurate, specific, and reliable.PMID 8146858Read ↗

Large-scale DRB and DQB1 oligonucleotide typing for the NMDP registry: progress report from year 2.Semantic proximity Read ↗

Complete analysis of HLA-DQB1 polymorphism and DR-DQ linkage disequilibrium by oligonucleotide typing.Semantic proximity Read ↗

Simultaneous genotyping of DRB1/3/4/5 loci by oligonucleotide microarray.Semantic proximity Read ↗

DRB3 alleles with variations in the annealing sites of commonly used amplification primers.Semantic proximity Read ↗

Strategies and technical challenges in allele level Class II typing in 2578 bone marrow transplantation donor-recipient pairs.Semantic proximity Read ↗

Sequence-specific priming and exonuclease-released fluorescence detection of HLA-DQB1 alleles.Semantic proximity Read ↗

Analysis of HLA class II polymorphism using polymerase chain reaction.Semantic proximity Read ↗

Selection of unrelated donors for bone marrow transplantation is improved by HLA class II genotyping with oligonucleotide hybridization.Semantic proximity Read ↗

Direct sequencing of SSP-PCR-amplified cDNA to identify new alleles in the DR52-associated DRB1 group: identification of DRB1*1115, DRB1*1117 and DRB1*1319.Semantic proximity Read ↗

HLA-DQA1 and HLA-DQB1 DNA typing in multiplex IDDM families by use of sequence-specific oligonucleotide probes and genomic sequencing.Semantic proximity Read ↗

Development and clinical evaluation of oligonucleotide microarray for HLA-AB genotyping.Semantic proximity Read ↗

Polymorphism of HLA-DRw52-associated DRB1 genes as defined by sequence-specific oligonucleotide probe hybridization and sequencing.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.