Article
Simultaneous genotyping of DRB1/3/4/5 loci by oligonucleotide microarray.
The Journal of molecular diagnostics : JMD - 1 Nov 2005
Bang-Ce Ye, Xiaohe Chu, Ye Fan, Songyang Li, Bincheng Yin, Peng Zuo
Abstract excerpt
Matching of the HLA antigens for donor-recipient in transplantation, disease predisposition or protection, population studies, and forensic testing requires accurate but simple typing methods. Here, we describe a DNA-based tissue-typing assay that determines the haplotype of the DRB1/3/4/5 loci in hy-bridization of oligonucleotide array after sample amplification. Using this multianalyte DNA hybridization system,...
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