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Article

Rapid detection of cytomegalovirus strains resistant to ganciclovir through mutations within the gene UL97.

Molecular and cellular probes - 1 Dec 1993

Alain S, Mazeron M C, Pépin J M, Morinet F, Raskine L, Sanson-Le Pors M J

Abstract excerpt

The human cytomegalovirus (HCMV) gene UL97 product was shown to play an important role in phosphorylation of ganciclovir (GCV) in HCMV-infected cells. The deletion of the 4 amino-acid sequence AACR confers resistance to a laboratory mutant. The aim of this study was to develop a rapid and simple method to detect mutations within the 12 base pair (bp) fragment encoding AACR, from isolates and clinical specimens...

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Source

Identifiers

PMID: 8145779
DOI: 10.1006/mcpr.1993.1072

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Rapid detection of cytomegalovirus strains resistant to ganciclovir through mutations within the gene UL97.PMID 8145779Read ↗

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