Article
Association of human class I MHC alleles with the adenovirus E3/19K protein.
Journal of immunology (Baltimore, Md. : 1950) - 15 Apr 1994
Beier D C, Cox J H, Vining D R, Cresswell P, Engelhard V H
Abstract excerpt
A panel of HLA-A and -B locus products was analyzed for their ability to associate with the adenovirus E3/19K (E19) protein in a co-immunoprecipitation assay. Three general categories of binding were identified. HLA-A2.1 and -B7 bind very well to E19. Compared with A2.1, 6- to 30-fold less E19 was associated with HLA-A3, -A1, and -Aw69; 50- to 150-fold less E19 was associated with HLA-Aw68, -B27, and -Bw58....
Topics
- Adenovirus Early Proteins
- Adenoviruses, Human
- Alleles
- Animals
- Antigens, Viral
- Genes, MHC Class I
- H-2 Antigens
- HLA-A Antigens
- Humans
- Mice
- Protein Binding
- Recombinant Fusion Proteins