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Article

The E1B 19K protein associates with lamins in vivo and its proper localization is required for inhibition of apoptosis.

Oncogene - 25 Sept 1997

Rao L, Modha D, White E

Abstract excerpt

Expression of the E1B 19K protein is required to inhibit apoptosis induced by E1A during adenovirus infection and transformation. E1B 19K is homologous to Bcl-2 in function and the two proteins also share limited amino acid sequence homology. Consequently, the E1B 19K and Bcl-2 proteins bind to and inhibit the cellular death-inducing proteins Bax, Bak and Nbk/Bik. Both E1B 19K and Bcl-2 localize to membranes of...

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Identifiers

PMID: 9380411
DOI: 10.1038/sj.onc.1201323

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The E1B 19K protein associates with lamins in vivo and its proper localization is required for inhibition of apoptosis.PMID 9380411Read ↗

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The E1B19K Oncoprotein Complexes with Beclin 1 to Regulate Autophagy in Adenovirus-Infected CellsSemantic proximity Read ↗

Lamin proteolysis facilitates nuclear events during apoptosis.Semantic proximity Read ↗

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Adenovirus E1B 19-kilodalton protein overcomes the cytotoxicity of E1A proteins.Semantic proximity Read ↗

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Requirements for the association of adenovirus type 2 E3/19K wild-type and mutant proteins with HLA antigens.Semantic proximity Read ↗

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