Requirements for the association of adenovirus type 2 E3/19K wild-type and mutant proteins with HLA antigens.

doi:10.1128/JVI.64.8.3679-3685.1990

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Article

Requirements for the association of adenovirus type 2 E3/19K wild-type and mutant proteins with HLA antigens.

Journal of virology - 1 Aug 1990

Gabathuler R, Lévy F, Kvist S

Abstract excerpt

The E3/19K protein of human adenovirus type 2 is a resident of the endoplasmic reticulum (ER). Immediately after synthesis, it associates with major histocompatibility complex class I antigens and prevents their intracellular transport and cell surface expression. We have generated several C-terminal deletion mutants of the E3/19K protein that are preterminated at various positions on both sides of the...

Topics

Adenovirus Early Proteins
Adenoviruses, Human
Amino Acid Sequence
Antigens, Viral, Tumor
Cell Line
Chromosome Deletion
Endoplasmic Reticulum
Glycosylation
HLA Antigens
Humans
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Oligonucleotide Probes

Oncogene Proteins, Viral

Protein Binding

Protein Conformation

Transfection

Source

Open in PubMed Open full text

Identifiers

PMID: 2142509
DOI: 10.1128/JVI.64.8.3679-3685.1990
PMCID: PMC249661

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2142509-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Requirements for the association of adenovirus type 2 E3/19K wild-type and mutant proteins with HLA antigens.PMID 2142509Read ↗

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