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Article

Requirements for the association of adenovirus type 2 E3/19K wild-type and mutant proteins with HLA antigens.

Journal of virology - 1 Aug 1990

Gabathuler R, Lévy F, Kvist S

Abstract excerpt

The E3/19K protein of human adenovirus type 2 is a resident of the endoplasmic reticulum (ER). Immediately after synthesis, it associates with major histocompatibility complex class I antigens and prevents their intracellular transport and cell surface expression. We have generated several C-terminal deletion mutants of the E3/19K protein that are preterminated at various positions on both sides of the...

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Identifiers

PMID: 2142509
DOI: 10.1128/JVI.64.8.3679-3685.1990
PMCID: PMC249661

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Source receipt: pubmed, retrieved 7 Sept 2026.

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Requirements for the association of adenovirus type 2 E3/19K wild-type and mutant proteins with HLA antigens.PMID 2142509Read ↗

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Structural analysis of the adenovirus type 2 E3/19K protein using mutagenesis and a panel of conformation-sensitive monoclonal antibodies.Semantic proximity Read ↗

Activation of transcription factor NF-kappaB by the adenovirus E3/19K protein requires its ER retention.Semantic proximity Read ↗

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A 20,500-Dalton protein is coded by region E3 of subgroup B but not subgroup C human adenoviruses.Semantic proximity Read ↗

The 19-amino acid cassette of cyclooxygenase-2 mediates entry of the protein into the endoplasmic reticulum-associated degradation system.Semantic proximity Read ↗

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Binding of human cytomegalovirus US2 to major histocompatibility complex class I and II proteins is not sufficient for their degradation.Semantic proximity Read ↗

The E1B19K Oncoprotein Complexes with Beclin 1 to Regulate Autophagy in Adenovirus-Infected CellsSemantic proximity Read ↗

The E1B 19,000-molecular-weight protein of group C adenoviruses prevents tumor necrosis factor cytolysis of human cells but not of mouse cells.Semantic proximity Read ↗

A 6700 MW membrane protein is encoded by region E3 of adenovirus type 2.Semantic proximity Read ↗

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