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Article

Activation of transcription factor NF-kappaB by the adenovirus E3/19K protein requires its ER retention.

The Journal of cell biology - 1 Feb 1996

Pahl H L, Sester M, Burgert H G, Baeuerle P A

Abstract excerpt

We have recently shown that the accumulation of diverse viral and cellular membrane proteins in the ER activates the higher eukaryotic transcription factor NF-kappaB. This defined a novel ER-nuclear signal transduction pathway, which is distinct from the previously described unfolded protein response (UPR). The well characterized UPR pathway is activated by the presence of un- or malfolded proteins in the ER. In...

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Identifiers

PMID: 8647884
DOI: 10.1083/jcb.132.4.511
PMCID: PMC2199876

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Activation of transcription factor NF-kappaB by the adenovirus E3/19K protein requires its ER retention.PMID 8647884Read ↗

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