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Article

Mutation and altered expression of p53 genes in experimental rat bladder tumor cells.

Molecular carcinogenesis - 1 Feb 1994

Jones R F, Matuszyk J, Debiec-Rychter M, Wang C Y

Abstract excerpt

p53 genes were analyzed for mutations and expression in a series of 24 tumors or hyperplastic lesions of the urinary bladder induced in F344 rats by carcinogen treatment. Of these, 18 were analyzed as short-term urothelial cultures. Polymerase chain reaction-single-strand conformation polymorphism analysis and DNA sequencing were used to detect alterations in p53 genes or cDNAs, and the relative amounts of p53...

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PMID: 8142014
DOI: 10.1002/mc.2940090207

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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