Article
Complementation of mutant and wild-type human mitochondrial DNAs coexisting since the mutation event and lack of complementation of DNAs introduced separately into a cell within distinct organelles.
Molecular and cellular biology - 1 Apr 1994
Yoneda M, Miyatake T, Attardi G
Abstract excerpt
The rules that govern complementation of mutant and wild-type mitochondrial genomes in human cells were investigated under different experimental conditions. Among mitochondrial transformants derived from an individual affected by the MERRF (myoclonus epilepsy associated with ragged red fibers) e...
Topics
- Base Sequence
- Cell Line
- Cell Line, Transformed
- Cells, Cultured
- Clone Cells
- DNA, Mitochondrial
- Genetic Complementation Test
- Genotype
- Humans
- MELAS Syndrome
- MERRF Syndrome
- Mitochondria, Muscle
- Molecular Sequence Data
- Muscles
- Oligodeoxyribonucleotides